The 2025 National Survey on Drug Use and Health counted 6.9 million individuals aged 12 and older misusing prescription opioids. Of that group, 4.0 million met the clinical criteria for opioid use disorder. Far fewer than this number ever get treatment. The breakdown by age shows where the problem is most concentrated.
| Age Group | Individuals Misusing Prescription Opioids |
| 12 to 17 years | 402,000 |
| 18 to 25 years | 733,000 |
| 26 and older | 5.7 million |
Opioids bind to receptors in your brain and spinal cord. They block pain signals and release dopamine simultaneously. The pain relief is why you were prescribed them. The dopamine is why some individuals keep taking them after the pain is gone.
Your brain adjusts fast. Within a few weeks of regular use, it produces less of its own natural painkillers. The medication is doing the job instead. Tolerance builds, so the dose that worked in week one does nothing by week six. Taking more feels like the obvious fix. Most individuals cross the line right there without ever deciding to do so.
Dependence is physical. Your body has adapted to the drug and reacts when you stop, which is why withdrawal happens. Someone on a legitimate long-term prescription can be dependent without being addicted. Their use follows the prescription and nothing else in their life is falling apart.
Addiction adds compulsion. You keep using despite consequences you can clearly see. You take more than prescribed, run out early, or find other ways to get pills. The drug starts driving decisions you would not otherwise make. Most individuals in our rehab for opioid addiction crossed from one to the other without noticing when.
Physical dependence shows up in the body first. You need higher doses for the same relief. Withdrawal shows up between doses or when you try to stop. Muscle aches, sweating, chills, nausea, restlessness, and poor sleep are common. Your body has adapted and reacts when the drug is not there.
Dependence, in itself, is neither a moral problem nor a sign of weakness. It happens to individuals taking medication exactly as directed. What matters is whether it stays contained. Trouble starts when it begins pulling work, relationships, and health down with it.
Addiction shows up in behavior, not just the body. Recognizing it early makes a real difference in how treatment goes. Here is what tends to show up:
Nobody shows all of these. If a handful of them fit your situation, an honest assessment tells you where things stand. Our team gives you a straight answer rather than a sales pitch. What you do with that answer is up to you.
The physical toll builds slowly. Chronic constipation, hormone disruption, and weakened immune function are common. Sleep quality drops, which makes everything else harder. Long-term use can also cause increased pain sensitivity, meaning the medication eventually makes the original problem worse.
Mentally, depression and anxiety are common companions. Opioids blunt emotional range over time, so nothing feels particularly good or bad. Memory and concentration decline. Combining opioids with alcohol or benzodiazepines raises overdose risk substantially, since all three slow breathing.
Medication support is coordinated through trusted medical partners rather than provided on-site. Buprenorphine and methadone reduce cravings and ease withdrawal. Naltrexone blocks opioid effects and lowers relapse risk. Which one fits depends on your history, other health conditions, and your own preference.
Medication is not the whole plan. It creates enough physical stability for the therapy to actually work. Neither piece does much alone. Our team coordinates directly with your prescriber so nothing falls through the cracks between providers.
Prescription opioid dependence responds well to outpatient treatment when the physical piece is handled properly. Our intensive outpatient program runs structured sessions several days a week while you keep living at home. Which approaches you get depends on your history and what the assessment shows. These are the ones we use most:
Chronic pain complicates opioid recovery in ways other substances do not. Many individuals still have a real medical problem after the addiction is treated. Our team works with your other providers on a pain plan that does not rely on opioids. Your team at Flatirons Denver adjusts your treatment as your pain and symptoms change.
Getting off opioids is not a willpower problem, and needing medical help is not a failure. Our admissions team at Flatirons Recovery will ask about your use and answer your questions. Insurance verification happens on that same call. We can tell you quickly whether opioid addiction treatment in Denver with us is a fit. Contact us today to get started.
Questions come up before treatment starts. Here are direct answers to what we hear most.
Chronic pain does not disappear because the addiction gets treated. Our team coordinates with your medical providers on non-opioid pain approaches so you are not left choosing between pain and recovery.
Only with your written permission. Coordinating with your prescriber usually helps your care, but that decision stays yours.
A supervised taper is often the safer approach, especially with long-term prescription use. Our assessment determines whether tapering or a different path fits your situation.
Acute withdrawal usually resolves within a week or two. Sleep, mood, and energy often take several months to stabilize fully, which is normal and not a sign of failure.
The underlying dependence works the same way, though the circumstances differ. Prescription opioid treatment often involves more coordination around ongoing pain management and existing medical relationships.